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Flordeliza S. Villaneuva, MD
Principles of Ultrasound Molecular Imaging
Flordeliza S. Villaneuva, MD
01/22/2011 | Time : 27 min
About This Lecture:

Topics mentioned in this video : Definition of molecular imaging, Prerequisites to in vivo molecular imaging, Molecular imaging targets, Molecular imaging targeting ligands confer specificity, Ultrasound molecular imaging: the concept, The target, The microbubble, The ideal targeted microbubble, Potential clinical applications, Leukocyte adhesion to activated endothelium, ICAM 1 co-localizes with early atherosclerosis lesions, Microbubble targeting, Proof of principle, ICAM 1 – targeted microbubble adherence, Heterotopic rat heart transplant, ICAM 1 – targeted microbubble detection of cardiac rejection, Atherosclerosis plaque detection, Clinical rationale for ischemic memory imaging, Basis for P-selectin targeting, Sialyl Lewis, Selectin-targeted microbubbles, Ultrasound ischemic memory imaging: selectin targeting, Clinical rationale for angiogenesis imaging, RRL, Targeted ultrasound can detect tumor vasculature, Ultrasound imaging of endogenous and therapeutic angiogenesis, Summary, Future work, Center for ultrasound molecular imaging and therapeutics

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Keywords : angiogenesis, Arg-Arg-Leu, atherosclerotic lesion, atherosclerotic plaque, CD54, Cluster of Differentiation 54, endothelial dysfunction, endothelium, ICAM 1, Inter-Cellular Adhesion Molecule 1, ischemic memory imaging, ligand, microbubble adherence, microbubble targeting, microbubbles, molecular imaging, molecular probe, molecular ultrasound, neovascularization, P-selectin targeting, RRL, Sialyl Lewis, targeting ligand, therapeutic angiogenesis, tripeptide sequence, tumor vasculature, ultrasound contrast agents

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