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Evan Ungar, MD, FACR
The Future: Targeted Microbubbles
Evan Ungar, MD, FACR
03/26/2012 | Time : 25 min
About This Lecture:

Topics mentioned in this video : The future: targeted microbubbles, Targeted MBs, Background, Targeted MB – design considerations, Ligand design considerations, Chart, Targeted imaging of TNF-alpha induced inflammation, Quantitating increases in backscatter, Targeted microbubbles – design, Targeted MBs - potential clinical indications, Molecular targets of angiogenesis in cancer, Anti-VEGF drugs, Current Phase II clinical trials of anti-angiogenesis drugs, BR55 targeted agent, Antiangiogenic cancer therapy, Chart, Cited literature, Sonographic images, Chart, Theranostics – imaging and therapy, Theranostics – practical considerations, Video clip, Acoustically active nanodroplets, Confocal microscopy, Internalization of nanodroplets, SCID mouse with prostate tumor, Video clip, Cavitation of microbubbles in sonothrombolysis, MB enhanced sonothrombolysis in canine model of myocardial infarction, Sonographic image, Sonolysis restores myocardial bloodflow post MI, In vitro human thrombus, PPP clots, Conclusions

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Keywords : angiongenesis, cavitation, CEUS, contrast enhanced ultrasound, mechanical index, MI, microbubbles, nanodroplets, sonolysis, sonothrombolysis, targeted microbubbles, theranostics, ultrasound contrast agents, vascular endothelial growth factor, VEGF

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