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Articles » Central nervous system » Holoprosencephaly » Semilobar

2004-10-15-14 Holoprosencephaly,semilobar © Bailleul

Holoprosencephaly, semilobar 

Patrick Bailleul, MD

This is a 22 week old fetus with semilobar holoprosencephaly and median cleft lip. The fetus had a normal karyotype and the pregnancy was terminated. The fetus shows the following features:

A dilated single ventricle and fused thalami:

Median cleft lip -

Photograph of the abortus:

Autopsy specimen of the brain with serial sections from front to back showing the 2 frontal lobes and their posterior fusion.

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