2010-2-18 Case the week #262 © Gourand www.thefetus.net/
Case of the week #262
February, 18, 2010 - March 4, 2010
Catherine Garel, MD*, Antoinette Bernabe Gelot, MD, PhD**, Marie-Laure Moutard, MD***, Romulus Grigorescu, MD****, Luc Gourand,MD*****.
* Radiology Department, Hopital A.Trousseau AP-HP
** Neuropathology Departement, Hopital A.Trousseau AP-HP
*** Neuropediatrics Department, Hopital A.Trousseau AP-HP
**** Foetopathology Department, Hopital A.Trousseau AP-HP
***** Maternité Les Bluets, Paris
Case report
The following images represent a rare brain anomaly which was diagnosed at 23 weeks of gestation.
A consanguineous 32-year old woman (G2P1, one healthy boy from the previous pregnancy), with non-contributive history (no diabetes, no teratogenic exposure) was referred to our unit at 23 weeks for a second opinion ultrasound examination regarding the cerebral structures of the fetus. No other anomaly (in the face or extremities) was found. Karyotype of the fetus was normal: 46 XY.
Ultrasound examination revealed the following findings:
Images 1-4: Ultrasound images at 23 weeks.
Images 5,6: Images show a Doppler imaging at 23 weeks.
Images 7-10: MRI at 23 weeks.
Images 11,12: Images 11,12 show the neuropathology specimen.
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